I-Niacinamideiwuhlobo lwe-vitamin B3 oluvame ukusetshenziswa emikhiqizweni yokunakekelwa kwesikhumba ngenxa yezinzuzo zalo ezahlukahlukene esikhumbeni. Omunye wemiphumela yalo ethandwa kakhulu ikhono layo lokukhanyisa nokukhanyisa isikhumba, okwenza kube yisithako esivamile emikhiqizweni ethengiswayo yokwenza isikhumba sibe mhlophe noma silungise ithoni yesikhumba. Kulo mbiko wokuhlolwa komzimba womuntu, sizohlola umphumela wokwenza isikhumba sibe mhlophe we-niacinamide.
Ukuhlolwa kwakubandakanya abahlanganyeli abangu-50 abahlukaniswe ngokungahleliwe baba amaqembu amabili: iqembu lokulawula kanye neqembu elisebenzisa umkhiqizo oqukethe i-5% niacinamide. Abahlanganyeli bayalwa ukuba bafake umkhiqizo ebusweni babo kabili ngosuku isikhathi esingamasonto ayi-12. Ekuqaleni kocwaningo kanye nasekupheleni kwesikhathi esingamasonto ayi-12, kwathathwa izilinganiso zesikhumba sabahlanganyeli kusetshenziswa i-colorimeter, elinganisa ubukhali bombala wesikhumba.
Imiphumela ibonise ukuthi kube nokuthuthuka okuphawulekayo kwesimo sesikhumba eqenjini elisebenzisai-niacinamideumkhiqizo uma uqhathaniswa neqembu lokulawula. Abahlanganyeli eqenjini le-niacinamide babonise ukwehla kombala wesikhumba, okubonisa ukuthi isikhumba sabo sesibe sikhanya futhi sikhanya phakathi nesikhathi samaviki ayi-12. Ngaphezu kwalokho, akukho miphumela emibi ebikwe yinoma yimuphi wabahlanganyeli kunoma yiliphi iqembu, okubonisa ukuthi i-niacinamide iyisithako esiphephile nesibekezelelwa kahle sokusetshenziswa emikhiqizweni yokunakekelwa kwesikhumba.
Le miphumela ihambisana nezifundo zangaphambilini ezibonise imiphumela yokukhanyisa isikhumba kanye nokukhanyisa kwe-niacinamide. I-Niacinamide isebenza ngokuvimbela ukukhiqizwa kwe-melanin, umbala onikeza isikhumba umbala waso. Lokhu kuyenza ibe yisithako esisebenzayo sokunciphisa i-hyperpigmentation, njengezindawo zokuguga noma i-melasma, kanye nokukhanyisa ithoni yesikhumba iyonke. Ngaphezu kwalokho, i-niacinamide iboniswe inezakhiwo zokulwa nokuvuvukala kanye ne-antioxidant, ezingasiza ekuvikeleni isikhumba ekulimaleni futhi zithuthukise impilo yaso iyonke kanye nokubukeka.
Ekuphetheni, lo mbiko wokuhlolwa komzimba womuntu unikeza ubufakazi obengeziwe bemiphumela yokukhanya kwesikhumba kanye nokukhanya.
Isikhathi sokuthunyelwe: Mashi-23-2023