I-ArbutinIngxenye eyenzeka ngokwemvelo etholakala kwimithombo yezitshalo ehlukahlukene efana ne-Bearberry, ama-cranberry, nama-blueberries. Ithole ukunakwa okuphawuleka kakhulu embonini yeSkincare ne-COSMET ngenxa yezakhiwo zayo ezingaba khona kanye nokukhanyisa. Umshini ongemuva kwemiphumela yamhlophe ye-Arbutin uzungeza amandla ayo okuvimbela umsebenzi we-enzyme ebizwa nge-tyrosinase, odlala indima ebaluleke kakhulu ekukhiqizeni isikhumba, izinwele, nombala wamehlo.
Umbala wesikhumba unqunywa ngenani kanye nokusatshalaliswa kwe-melanin ekhiqizwa yi-melanocytes, amaseli akhethekile ku-Enidermal ungqimba. I-Tyrosinase iyi-enzyme ebalulekile ku-melanin synthesis yendlela, i-catalyzing ukuguqulwa kwe-amino acid tyrosine ku-melanin eyandulelayo, okugcina kuholela ekwakhekeni kwemibala ye-melanin. U-Arbutin unamandla amhlophe amhlophe ngokuyinhloko ngokuvinjwa kokuncintisana kwe-tyrosinase umsebenzi.
U-Arbutin uqukethe isibopho se-glycoside, okuwukuxhumana kwamakhemikhali phakathi kwe-molecule kashukela kanye ne-hydroquinone molecule. IHydroquinone iyindawo eyaziwayo enezakhiwo ezikhanyisa isikhumba, kepha kungaba nzima esikhunjeni futhi ihlotshaniswa nemiphumela emibi engaba khona. Ngakolunye uhlangothi, i-Arbutin, isebenza njengenye indlela ye-Hydroquinone ngenkathi isanikeza imvume yokukhiqizwa okusebenzayo kwe-melanin.
Lapho i-Arbutin isetshenziswa esikhunjeni, imunwe futhi ifakwe ku-hydroquinone ngezinqubo ze-enzymatic. Le Hydroquinone yavimbela ukuncintisana kwesenzo seTyrosinase ngokuthatha indawo yayo esebenzayo. Ngenxa yalokhu, ama-molecule angama-tyrosine awakwazi ukuguqulwa ngempumelelo abe yi-melanin wandulele, okuholela ekukhiqizeni okunciphile kuka-melanin. Lokhu kugcina kuphumela ekunciphisweni kancane kancane ku-Skin Pigmentation, okuholela ekukhanyeleni okulula nokuningi ngisho nesikhumba.
Kubalulekile ukuqaphela lokhoUmhlophe ka-Arbutinimiphumela ayikabi ngokushesha. Ukushintshwa kwesikhumba kuthatha cishe inyanga, ukusetshenziswa okungaguquguquki futhi okuhlala isikhathi eside kwemikhiqizo equkethe i-arbutin kuyadingeka ukubuka ushintsho olubonakalayo ku-Skin Pigmentation. Ngaphezu kwalokho, indlela yokusebenza ye-Arbutin isebenza kangcono kakhulu ekubhekaneni nezinkinga ezihlobene ne-hyperpigmentation, njengezindawo zobudala, izindawo zelanga, kanye ne-melasma, esikhundleni sokushintsha umbala wesikhumba.
Iphrofayili yezokuphepha ye-Arbutin ngokuvamile ibekezelelwa kangcono kunabanye abasebenza ngezikhumba, okwenza kube yisinqumo esithandwayo sabantu abafuna ukubhekana nethoni yesikhumba engalingani. Kodwa-ke, ukuphendula komuntu ngamunye kungahluka, futhi kungakuhle ukwenza ukuhlolwa kwe-patch ngaphambi kokufaka imikhiqizo emisha ye-skincare kwinqubo yakho.
Ekuphetheni, indlela eyandayo yesikhumba ye-Arbutin ithembela emandleni ayo okuvimbela umsebenzi we-tyrosinase, okuholela ekunciphiseni ukukhiqizwa kwe-melanin. Ukuvinjwa kwayo okuncintisanayo kwe-tyrosinase, okuholela ekunciphiseni i-melanin synnensis, kwenza kube yisithako esithandekayo emikhiqizweni ye-skincare okuqondiswe kwi-hyperpigmentation nethoni yesikhumba engalingani. Njenganoma iyiphi i-skincare isithako, kunconywa ukuthi uthintane nodokotela wesikhumba ngaphambi kokwethula imikhiqizo emisha kwinqubo yakho, ikakhulukazi uma unezinto ezikhathazayo zesikhumba noma izimo ezithile.
Isikhathi sePosi: Aug-30-2023