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Ukusetshenziswa kwe-antibacterial ye-cinnamaldehyde emaphaketheni okudla

I-Cinnamaldehyde yenza u-85% ~ 90% wamafutha abalulekile e-sinamoni, kanti i-China ingenye yezindawo eziyinhloko zokutshala isinamoni, kanti izinsiza ze-cinnamaldehyde zicebile.Isakhiwo samangqamuzana iCinnamaldehyde (C9H8O) iyiqembu le-phenyl elixhunywe ku-acrylein, esesimweni semvelo soketshezi olukhanyayo oluphuzi noma oluphuzi olunsundu, olunokunambitheka okuyingqayizivele neqinile kwesinamoni kanye ne-coke, lungasetshenziswa ezingomeni nasezindaweni zokugcoba.Njengamanje, kube nemibiko eminingi mayelana nesenzo se-antibacterial esibanzi se-cinnamaldehyde kanye nendlela yayo, futhi izifundo zibonise ukuthi i-cinnamaldehyde inomphumela omuhle we-antibacterial ku-bacterium nesikhunta.Emkhakheni wezokwelapha, ezinye izifundo zibuyekeze inqubekelaphambili yocwaningo lwe-cinnamaldehyde ezifweni ze-metabolic, izifo zesistimu yokujikeleza kwegazi, i-anti-tumor nezinye izici, futhi zathola ukuthi i-cinnamaldehyde ine-anti-diabetes enhle, i-anti-obesity, i-anti-tumor nezinye. imisebenzi yemithi.Ngenxa yemithombo yayo ecebile, izithako zemvelo, ukuphepha, ubuthi obuphansi, ukunambitheka okuyingqayizivele kanye nomphumela obanzi we-antibacterial, kuyisithasiselo sokudla esigunyazwe i-United States Food and Drug Administration kanye ne-China.Nakuba inani eliphezulu alikhawulelwe ekusetshenzisweni, ukuguquguquka kwayo kanye nephunga elimnandi kunciphisa ukusetshenziswa kwalo okubanzi ekudleni.Ukulungisa i-cinnamaldehyde efilimini yokupakisha ukudla kungathuthukisa ukusebenza kahle kwayo kwe-antibacterial futhi kunciphise umthelela wezinzwa ekudleni, futhi kubambe iqhaza ekuthuthukiseni ikhwalithi yokugcinwa kokudla kanye nokuthutha kanye nokwandisa impilo yeshalofu.

1. I-antibacterial composite membrane matrix

Iningi locwaningo ngefilimu yokupakisha ye-antibacterial yokudla isebenzisa izinto zemvelo nezimoshekayo njenge-matrix eyenza ifilimu, futhi ifilimu yokupakisha ilungiswa ngokumboza, ukuphonsa noma indlela yokushisa ephezulu ye-extrusion.Ngenxa yemodi ehlukene yesenzo nokuhambisana phakathi kwama-membrane substrates ahlukene kanye nezinto ezisebenzayo, izakhiwo ze-membrane eziqediwe zihlukile, ngakho-ke kubaluleke kakhulu ukukhetha i-membrane substrate efanele.Ama-substrates akha ifilimu asetshenziswa kakhulu ahlanganisa izinto zokwenziwa ezibolayo ezifana ne-polyvinyl alcohol ne-polypropylene, izinto zemvelo ezifana nama-polysaccharides namaprotheni, nezinto eziyinhlanganisela.I-Polyvinyl alcohol (PVA) iyi-polymer ewumugqa, evamise ukwakha uhlaka lwenethiwekhi olunezinhlangothi ezintathu lapho ixhunywe ku-crosslink, futhi inezakhiwo ezinhle kakhulu zemishini kanye nezakhiwo zokuvimbela.Izinsiza ze-membrane zemvelo ezifana ne-matrix ziningi futhi zitholakala kabanzi.Isibonelo, i-polylactic acid ingavutshelwa ngezinto ezingavuthiwe ezifana nesitashi nommbila, onemithombo eyanele nevuselelekayo, i-biodegradability enhle kanye ne-biocompatibility, futhi iyinto ekahle yokupakisha evumelana nemvelo.I-matrix eyinhlanganisela ivamise ukwakhiwa ngama-membrane matrices amabili noma ngaphezulu, angadlala indima ehambisanayo uma kuqhathaniswa ne-membrane matrix eyodwa.

Izakhiwo zemishini kanye nezakhiwo zokuvimbela ziyizinkomba ezibalulekile zokuhlola ukufaneleka kwefilimu yokupakisha.Ukwengezwa kwe-cinnamaldehyde kuzoxhumanisa ne-polymer membrane matrix futhi ngaleyo ndlela kunciphise uketshezi lwamangqamuzana, ukwehla kobude ngesikhathi sekhefu kungenxa yokungaqhubeki kwesakhiwo senethiwekhi ye-polysaccharide, kanye nokwanda kwamandla okuqinile kungenxa yokwanda kweqembu le-hydrophilic. ngesikhathi sokwenza ifilimu okubangelwa ukwengezwa kwe-cinnamaldehyde.Ngaphezu kwalokho, ukuvuthwa kwegesi kolwelwesi oluyinhlanganisela ye-cinnamaldehyde ngokuvamile kwanda, okungenzeka kube ngenxa yokuhlakazeka kwe-cinnamaldehyde ku-polymer ukuze kwakhiwe ama-pores, ama-voids namashaneli, ukunciphisa ukumelana nokudluliswa okukhulu kwama-molecule amanzi, futhi ekugcineni kuholele ekwandeni Ukungena kwegesi kulwelwesi oluyinhlanganisela ye-cinnamaldehyde.Izakhiwo zemishini kanye nokungena kwezingqimba eziningana ezihlanganisiwe ziyafana, kodwa ukwakheka kanye nezakhiwo ze-polymer substrates ezahlukene zihlukile, futhi ukusebenzisana okuhlukile ne-cinnamaldehyde kuzothinta ukusebenza kwefilimu yokupakisha, bese kuthinta ukusetshenziswa kwayo, ngakho-ke kubaluleke kakhulu. ukukhetha i-polymer substrate efanele kanye nokugxila.

Okwesibili, i-cinnamaldehyde kanye nendlela yokubopha ifilimu yokupakisha

Nokho, i-cinnamaldehyde inyibilika kancane emanzini ngokuncibilika okungu-1.4 mg/mL kuphela.Nakuba ubuchwepheshe bokuhlanganisa bulula futhi bufaneleka, izigaba ezimbili ze-cinnamaldehyde encibilikayo kumafutha kanye ne-membrane matrix encibilika emanzini azizinzile, futhi izinga lokushisa eliphezulu nezimo zokucindezela okukhulu ngokuvamile ezidingekayo enqubweni yokwenza ifilimu kunciphisa kakhulu ukugcwala kwe-cinnamaldehyde etholakalayo ulwelwesi.Kunzima ukufeza umphumela omuhle we-bacteriostatic.Ubuchwepheshe bokushumeka inqubo yokusebenzisa okubalulekile odongeni ukugoqa noma ukukhangisa into esebenzayo edinga ukushumeka ukuze kuhlinzekwe ukwesekwa kokusebenza noma ukuvikelwa kwamakhemikhali.Ukusetshenziswa kobuchwepheshe bokushumeka ukulungisa i-cinnamaldehyde kumpahla yokupakisha kungayenza iphume kancane, ithuthukise izinga lokugcinwa, kunwebe ukuguga kwefilimu okulwa namagciwane, futhi kuthuthukise izakhiwo zemishini yefilimu yokupakisha.Njengamanje, izindlela ezivamile zokwakha umthwali wokuhlanganisa i-cinnamaldehyde nefilimu yokupakisha zingahlukaniswa zibe izigaba ezimbili: ukwakhiwa komthwali wokufakelwa kanye nokwakhiwa komthwali wemvelo, okufaka ukushumeka kwe-polymer, ukushumeka kwe-nano liposome, ukushumeka kwe-cyclodextrin, ukubopha kobumba be-nano noma ukulayisha.Ngokuhlanganiswa kokuzihlanganisa kongqimba kanye ne-electrospinning, isithwali sokulethwa kwe-cinnamaldehyde singathuthukiswa, futhi imodi yesenzo kanye nobubanzi bokusetshenziswa kwe-cinnamaldehyde kungathuthukiswa.

Ukusetshenziswa kwefilimu yokupakisha ye-sinamoni aldehyde esebenzayo

Izinhlobo ezahlukene zokudla zinokuqukethwe kwamanzi ahlukene, ukwakheka kwezakhi kanye nezimo zokugcinwa nezokuthutha, futhi amandla okukhula kwama-spoilage microorganisms ahluke kakhulu.Umphumela wokulondolozwa kwe-cinnamaldehyde antibacterial packaging wokudla okuhlukene nawo uhlukile.

1. Ukugcina umphumela omusha emifino nezithelo

I-China inothile emithonjeni yemvelo, phakathi kwayo ukukhiqizwa nokusetshenziswa kwemakethe kwemifino nezithelo kukhulu.Kodwa-ke, umswakama kanye noshukela wemifino nezithelo kuphezulu, kunomsoco, futhi kujwayele ukungcoliswa kwamagciwane kanye nokuwohloka ngesikhathi sokugcinwa, ukuthutha nokuthengisa.Njengamanje, ukusetshenziswa kwefilimu yokupakisha elwa namagciwane kuyindlela ebalulekile yokuthuthukisa ikhwalithi yokugcinwa nokuhamba kwemifino nezithelo nokwandisa impilo yabo yeshalofu.Ukupakishwa kwefilimu eyinhlanganisela ye-cinnamaldehyde-polylactic acid yama-apula kunganciphisa ukulahleka kwemisoco, kuvimbele ukukhula kwe-rhizopus, futhi kwandise isikhathi sokugcinwa kwama-apula sibe yizinsuku eziyi-16.Lapho ifilimu yokupakisha esebenzayo ye-cinnamaldehyde isetshenziswa ekufakweni kwezaqathi ezisikiwe, ukukhula kwesikhunta nemvubelo kuvinjelwe, izinga lokubola kwemifino lancishiswa, futhi impilo yeshalofu yandiswa yaba yi-12d.

2. Umphumela wokugcina wokugcina wemikhiqizo yenyama Ukudla kwenyama kucebile ngamaprotheni, amafutha nezinye izinto, kunomsoco kanye nokunambitheka okuyingqayizivele.Emazingeni okushisa asekamelweni, ukukhiqizwa kwama-microorganisms kubangela ukubola kwamaprotheni enyama, ama-carbohydrate namafutha, okuholela ekonakaleni kwenyama, indawo enamathelayo, umbala omnyama, ukulahlekelwa ukunwebeka, kanye nephunga elibi.Ifilimu ye-Cinnamaldehyde esebenzayo yokupakisha ukudla isetshenziswa kabanzi ekufakweni kwengulube nenhlanzi, ivimbela ikakhulukazi ukukhula kwe-Staphylococcus aureus, i-Escherichia coli, i-aeromonas, imvubelo, amagciwane e-lactic acid namanye amagciwane, futhi inganweba impilo yeshalofu ye-8 ~ 14d.

3. Ukugcinwa okusha kwemikhiqizo yobisi Njengamanje, ukusetshenziswa kwemikhiqizo yobisi eShayina kuyanda unyaka nonyaka.Ushizi umkhiqizo wobisi oluvutshiwe onenani elicebile lokudla okunempilo kanye namaprotheni.Kodwa ushizi unokuphila okufushane kweshelufu, futhi izinga lokulahla emazingeni okushisa aphansi lisashaqisa.Ukusetshenziswa kwefilimu yokupakisha ye-cinnamic aldehyde kungandisa ngempumelelo impilo yeshalofu likashizi, kuqinisekise ukunambitheka okuhle kukashizi, futhi kuvimbele ukuwohloka kwe-cheese rancid.Ezingcezu zikashizi namasoso kashizi, isikhathi seshalofu sinwetshwa sibe yizinsuku ezingama-45 kanye nezinsuku ezingama-26 ngokulandelana ngemva kokusebenzisa ukupakisha okusebenzayo kwe-cinnamaldehyde, okusiza ekongeni izinsiza.

4. Umphumela wokugcina wokugcina wesinkwa sokudla kwesitashi kanye nekhekhe yimikhiqizo yesitashi, eyenziwe ngokucubungula ufulawa kakolweni, ukotini othambile kaphayini, omnandi futhi omnandi.Kodwa-ke, isinkwa nekhekhe kuneshelufu yesikhathi esifushane futhi kulula ukungcoliswa yisikhunta ngesikhathi sokuthengisa, okuholela ekuwohlokeni kwekhwalithi kanye nokumoshakala kokudla.Ukusetshenziswa kokupakishwa kokudla okusebenzayo kwe-cinnamaldehyde ekhekheni lesipontshi nesinkwa esisikiwe kungavimbela ukukhula nokusakazeka kwe-penicillium nesikhunta esimnyama, futhi kwandise impilo yeshalofu ku-10 ~ 27d, ngokulandelana.

 

I-Cinnamaldehyde inezinzuzo zomthombo omningi, i-bacteriostasis ephezulu kanye nobuthi obuphansi.Njenge-ejenti ye-bacteriostasis ekufakweni okusebenzayo kokudla, ukuzinza nokukhululwa kancane kwe-cinnamaldehyde kungathuthukiswa ngokwakha kanye nokwenza kahle isithwali sokudiliva, esibaluleke kakhulu ekuthuthukiseni ikhwalithi yokugcina kanye neyokuthutha yokudla okusha kanye nokwelula impilo yeshalofu lokudla.Eminyakeni yamuva nje, i-cinnamaldehyde yenze izimpumelelo eziningi kanye nenqubekela phambili ocwaningweni lokulondolozwa kokupakishwa kokudla, kodwa ucwaningo oluhlobene nesicelo lusasesigabeni sokuqala, futhi kusenezinkinga ezithile okufanele zixazululwe.Ngokucwaninga okuqhathanisayo kwemiphumela yabathwali abahlukene bokuletha kuzakhiwo zemishini kanye nezakhiwo zesithiyo ze-membrane, ukuhlola okujulile kwemodi yesenzo se-cinnamaldehyde kanye nomthwali kanye ne-kinetics yokukhululwa ezindaweni ezahlukene, ukutadisha umthelela womthetho wokukhula. Ama-microorganisms ekudleni ekonakaleni kokudla, kanye nendlela yokulawula yokupakishwa kwe-antibacterial ngesikhathi kanye nesivinini sokukhululwa kwama-antimicrobial agents.Dala futhi uthuthukise amasistimu okupakisha asebenzayo angahlangabezana nezidingo ezahlukene zokulondoloza ukudla.

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Isikhathi sokuthumela: Jan-03-2024