I-Cinnamaldehyde ikhiqiza u-85% ~ 90% wamafutha abalulekile esinamoni, kanti iShayina ingenye yezindawo eziyinhloko zokutshala isinamoni, futhi izinsiza ze-cinnamaldehyde zicebile. Isakhiwo sama-molecule e-Cinnamaldehyde (C9H8O) yiqembu le-phenyl elixhunywe ku-acrylein, esimweni semvelo soketshezi oluphuzi noma oluphuzi olunsundu oluthambile, olunephunga eliyingqayizivele nelinamandla le-sinamoni ne-coke, lingasetshenziswa ezinongo nasezithambisweni. Njengamanje, kube nemibiko eminingi ngesenzo se-cinnamaldehyde sokulwa namagciwane esibanzi kanye nendlela esebenza ngayo, futhi izifundo zikhombisile ukuthi i-cinnamaldehyde inomphumela omuhle wokulwa namagciwane kumabhaktheriya kanye nesikhunta. Emkhakheni wezokwelapha, ezinye izifundo zibukeze inqubekela phambili yocwaningo lwe-cinnamaldehyde ezifweni ze-metabolic, izifo zesistimu yokujikeleza kwegazi, ukulwa nomdlavuza kanye nezinye izici, futhi zathola ukuthi i-cinnamaldehyde inomphumela omuhle wokulwa nesifo sikashukela, ukulwa nokukhuluphala, ukulwa nomdlavuza kanye neminye imisebenzi yezokwelapha. Ngenxa yemithombo yayo ecebile, izithako zemvelo, ukuphepha, ubuthi obuphansi, ukunambitheka okuyingqayizivele kanye nomphumela we-antibacterial we-spectrum ebanzi, iyisengezo sokudla esivunyelwe yi-United States Food and Drug Administration kanye ne-China. Nakuba inani eliphezulu linganqunyelwe ukusetshenziswa, ukuguquguquka kwayo kanye nephunga elibi kunciphisa ukusetshenziswa kwayo okubanzi ekudleni. Ukulungisa i-cinnamaldehyde efilimini yokupakisha ukudla kungathuthukisa ukusebenza kwayo okulwa namagciwane futhi kunciphise umthelela wayo wokuzwa ekudleni, futhi kudlale indima ekuthuthukiseni ikhwalithi yokugcina nokuthutha ukudla kanye nokwandisa isikhathi sokuphila.
1. I-matrix ye-membrane ehlanganisiwe yokulwa namagciwane
Iningi locwaningo ngefilimu yokupakisha ukudla elwa namagciwane isebenzisa izinto zemvelo nezibolayo njenge-matrix eyakha ifilimu, kanti ifilimu yokupakisha ilungiswa ngendlela yokumboza, ukuphonsa noma indlela yokukhipha ukushisa okuphezulu. Ngenxa yendlela ehlukene yokusebenza kanye nokuhambisana phakathi kwe-substrates ezahlukene ze-membrane nezinto ezisebenzayo, izakhiwo ze-membrane eqediwe zihlukile, ngakho-ke kubaluleke kakhulu ukukhetha i-substrate ye-membrane efanele. Izakhiwo ezivame ukusetshenziswa ezakha ifilimu zifaka izinto ezibolayo zokwenziwa njenge-polyvinyl alcohol ne-polypropylene, izinto zemvelo njenge-polysaccharides namaprotheni, kanye nezinto ezihlanganisiwe. I-Polyvinyl alcohol (PVA) iyi-polymer eqondile, evame ukwakha isakhiwo senethiwekhi esinezinhlangothi ezintathu uma ixhunywe, futhi inezakhiwo ezinhle kakhulu zemishini kanye nezakhiwo zokuvimbela. Izinsiza zemvelo ezifana ne-membrane-like matrix ziningi futhi zitholakala kabanzi. Isibonelo, i-polylactic acid ingavutshelwa ngezinto zokusetshenziswa ezifana nesitashi nommbila, enemithombo eyanele nevuselelekayo, ukubola okuhle kanye nokuhambisana kwezinto eziphilayo, futhi iyinto yokupakisha efanelekile enobungani nemvelo. I-composite matrix ivame ukwakhiwa ngama-membrane matrices amabili noma ngaphezulu, angadlala indima ehambisanayo uma kuqhathaniswa ne-membrane matrix eyodwa.
Izakhiwo zemishini kanye nezakhiwo zokuvimbela ziyizinkomba ezibalulekile zokuhlola ukufaneleka kwefilimu yokupakisha. Ukwengezwa kwe-cinnamaldehyde kuzohlangana ne-polymer membrane matrix ngaleyo ndlela kunciphise ukugeleza kwama-molecule, ukwehla kobude lapho kuphuka kungenxa yokungaqhubeki kwesakhiwo senethiwekhi ye-polysaccharide, kanye nokwanda kwamandla okudonsa kungenxa yokwanda kweqembu le-hydrophilic ngesikhathi senqubo yokwakha ifilimu okubangelwa ukwengezwa kwe-cinnamaldehyde. Ngaphezu kwalokho, ukugeleza kwegesi kwe-cinnamaldehyde composite membrane ngokuvamile kwanda, okungase kube ngenxa yokusabalala kwe-cinnamaldehyde ku-polymer ukudala ama-pores, ama-voids kanye neziteshi, ukunciphisa ukumelana kokudluliselwa kwesisindo sama-molecule amanzi, futhi ekugcineni kuholele ekwandeni kokugeleza kwegesi kwe-cinnamaldehyde composite membrane. Izakhiwo zemishini kanye nokugeleza kwama-membrane amaningana ahlanganisiwe kuyafana, kodwa isakhiwo kanye nezakhiwo zama-substrate ahlukene e-polymer zihlukile, futhi ukusebenzisana okuhlukile ne-cinnamaldehyde kuzothinta ukusebenza kwefilimu yokupakisha, bese kuthinta ukusetshenziswa kwayo, ngakho-ke kubaluleke kakhulu ukukhetha i-substrate ye-polymer efanele kanye nokuhlushwa.
Okwesibili, indlela yokubopha ifilimu yokubopha i-cinnamaldehyde kanye ne-packaging
Kodwa-ke, i-cinnamaldehyde incibilika kancane emanzini futhi incibilika ngo-1.4 mg/mL kuphela. Nakuba ubuchwepheshe bokuxuba bulula futhi bulula, izigaba ezimbili ze-cinnamaldehyde encibilika ngamafutha kanye ne-membrane-soluble matrix ye-membrane azizinzile, futhi izinga lokushisa eliphezulu kanye nezimo zokucindezela okuphezulu ezivame ukudingeka enkambisweni yokwakha ifilimu zinciphisa kakhulu ukugcwala kwe-cinnamaldehyde etholakalayo ku-membrane. Kunzima ukufeza umphumela ofanele we-bacteriostatic. Ubuchwepheshe bokufaka buyinqubo yokusebenzisa izinto zodonga ukugoqa noma ukumunca into esebenzayo edinga ukufakwe ukuze inikeze ukwesekwa kokusebenza noma ukuvikelwa kwamakhemikhali. Ukusetshenziswa kobuchwepheshe bokufaka ukulungisa i-cinnamaldehyde ezintweni zokupakisha kungenza ukukhishwa kwayo kube kancane, kuthuthukise izinga lokugcina, kwandise ukuguga kwefilimu okulwa namagciwane, futhi kuthuthukise izakhiwo zemishini zefilimu yokupakisha. Njengamanje, izindlela ezivamile zokwakha i-cinnamaldehyde zokuhlanganisa i-cinnamaldehyde nefilimu yokupakisha zingahlukaniswa ngezigaba ezimbili: ukwakhiwa kwe-carrier yokwenziwa kanye nokwakhiwa kwe-carrier yemvelo, kufaka phakathi ukushumeka kwe-polymer, ukushumeka kwe-nano liposome, ukushumeka kwe-cyclodextrin, ukubopha kwe-nano clay noma ukulayisha. Ngokuhlanganisa ukuhlanganiswa kwezingqimba kanye nokujikeleza nge-electro, isithwali sokulethwa kwe-cinnamaldehyde singathuthukiswa, futhi imodi yesenzo kanye nobubanzi bokusetshenziswa kwe-cinnamaldehyde kungathuthukiswa.
Ukusetshenziswa kwefilimu yokupakisha ukudla esebenzayo yesinamoni aldehyde
Izinhlobo ezahlukene zokudla zinokuqukethwe kwamanzi okuhlukile, ukwakheka kwezakhamzimba kanye nezimo zokugcina nezokuthutha, futhi amandla okukhula kwamagciwane angcolisayo ahlukile kakhulu. Umphumela wokulondolozwa kokupakishwa kwe-cinnamaldehyde antibacterial kokudla okuhlukene nawo uhlukile.
1. Umphumela wokugcina imifino nezithelo zihlanzekile
IShayina icebile ngezinsiza zemvelo, phakathi kwazo ukukhiqizwa nokusetshenziswa kwemifino nezithelo emakethe kukhulu. Kodwa-ke, umswakama noshukela wemifino nezithelo kuphezulu, kucebile ngokudla okunempilo, futhi kuthambekele ekungcolisweni kwamagciwane kanye nokuwohloka ngesikhathi sokugcina, ukuthutha kanye nokuthengisa. Njengamanje, ukusetshenziswa kwefilimu yokupakisha elwa namagciwane kuyindlela ebalulekile yokuthuthukisa ikhwalithi yokugcina kanye nokuthutha yemifino nezithelo nokwandisa isikhathi sayo sokuphila eshalofini. Ukufakwa kwefilimu ehlanganisiwe ye-cinnamaldehyde-polylactic acid yama-apula kunganciphisa ukulahleka kwezakhamzimba, kuvimbele ukukhula kwe-rhizopus, futhi kwandise isikhathi sokugcina sama-apula sibe yizinsuku ezingu-16. Lapho ifilimu yokupakisha yokudla esebenzayo ye-cinnamaldehyde isetshenziswa ekufakweni kwekaroti okusha okusikiwe, ukukhula kwesikhunta kanye nemvubelo kwavinjelwa, izinga lokubola kwemifino lancishiswa, futhi isikhathi sokuphila eshalofini sandiswa saba yizinsuku ezingu-12.
2. Umphumela wokugcina okusha wemikhiqizo yenyama Ukudla kwenyama kucebile ngamaprotheni, amafutha nezinye izinto, kucebile ngokudla okunempilo kanye nokunambitheka okuyingqayizivele. Ezingeni lokushisa legumbi, ukukhiqizwa kwama-microorganisms kubangela ukubola kwamaprotheni enyama, ama-carbohydrate namafutha, okuholela ekonakaleni kwenyama, ubuso obunamathelayo, umbala omnyama, ukulahlekelwa ukunwebeka, kanye nephunga elibi. Ifilimu yokupakisha ukudla esebenzayo ye-Cinnamaldehyde isetshenziswa kabanzi ekupakisheni kwengulube nenhlanzi, ikakhulukazi ivimbela ukukhula kwe-Staphylococcus aureus, i-Escherichia coli, i-aeromonas, imvubelo, amabhaktheriya e-lactic acid kanye namanye amabhaktheriya, futhi ingandisa impilo yeshelufu yezinsuku ezingu-8 ~ 14.
3. Umphumela wokugcina imikhiqizo yobisi ihlanzekile Njengamanje, ukusetshenziswa kwemikhiqizo yobisi eShayina kuyanda unyaka nonyaka. Ushizi uwumkhiqizo wobisi obilisiwe onenani elicebile lokudla okunomsoco kanye namaprotheni. Kodwa ushizi uhlala isikhathi esifushane eshalofini, futhi izinga lokungcola emazingeni okushisa aphansi lisathusa. Ukusetshenziswa kwefilimu yokufaka ukudla ye-cinnamic aldehyde kungandisa ngempumelelo impilo yeshalofu yoshizi, kuqinisekise ukunambitheka okuhle koshizi, futhi kuvimbele ukuwohloka koshizi. Ngezingcezu zoshizi kanye nama-sauces oshizi, isikhathi seshalofu sandiswa sibe yizinsuku ezingu-45 kanye nezinsuku ezingu-26 ngokulandelana ngemuva kokusebenzisa i-cinnamaldehyde esebenzayo epaketheni, okusiza ukonga izinsiza.
4. Umphumela wokugcina ukudla kwesitashi isinkwa nekhekhe kuyimikhiqizo yesitashi, eyenziwe ngokucubungula ufulawa kakolweni, ukotini wephayini othambile, omnandi futhi omnandi. Kodwa-ke, isinkwa nekhekhe zihlala isikhathi esifushane eshalofini futhi zisengozini yokungcoliswa yisikhunta ngesikhathi sokuthengisa, okuholela ekuwohlokeni kwekhwalithi kanye nokulahlwa kokudla. Ukusetshenziswa kwe-cinnamaldehyde ekupakisheni kokudla okusebenzayo ekhekheni lesiponji kanye nesinkwa esisikiwe kungavimbela ukukhula nokusabalala kwe-penicillium kanye nesikhunta esimnyama, futhi kwandise isikhathi seshalofu sibe yizinsuku eziyi-10 ~ 27 ngokulandelana.
I-Cinnamaldehyde inezinzuzo zomthombo omningi, i-bacteriostasis ephezulu kanye nobuthi obuphansi. Njenge-ejenti ye-bacteriostasis ekupakisheni okusebenzayo kokudla, ukuzinza nokukhululwa kancane kwe-cinnamaldehyde kungathuthukiswa ngokwakha nokwenza ngcono isithwali sokulethwa, okubaluleke kakhulu ekuthuthukiseni ikhwalithi yokugcina nokuthutha kokudla okusha nokwandisa impilo yokudla eshalofini. Eminyakeni yamuva nje, i-cinnamaldehyde yenze izimpumelelo eziningi kanye nentuthuko ocwaningweni lokulondolozwa kokupakisha kokudla, kodwa ucwaningo oluhlobene nokusetshenziswa lusesesigabeni sokuqala, futhi kusenezinkinga ezithile okufanele zixazululwe. Ngokutadisha okuqhathanisayo kwemiphumela yezithwali zokulethwa ezahlukene ezakhiweni zemishini kanye nezakhiwo zokuvimbela ze-membrane, ukuhlola okujulile indlela yokusebenza kwe-cinnamaldehyde kanye nesithwali kanye ne-kinetics yokukhululwa kwayo ezindaweni ezahlukene, ukutadisha ithonya lomthetho wokukhula kwama-microorganisms ekudleni ekonakaleni kokudla, kanye nendlela yokulawula yokupakisha ama-antibacterial ngesikhathi kanye nesivinini sokukhululwa kwama-antimicrobial agents. Dala futhi uthuthukise izinhlelo zokupakisha ezisebenzayo ezingahlangabezana nezidingo ezahlukene zokulondolozwa kokudla.
Isikhathi sokuthunyelwe: Jan-03-2024