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Konke Odinga Ukukwazi NgeGlutaraldehyde

Njenge-saturated straight-chain aliphatic dibasic aldehyde, i-glutaraldehyde iwuketshezi olungenambala olusobala olunephunga elicasulayo kanye nomphumela omuhle kakhulu wokubulala kumagciwane okuzala, amagciwane, i-mycobacteria, isikhunta se-pathogenic kanye nebhaktheriya yebhaktheriya, kanye ne-non-oxidizing wide-spectrum bactericide.I-Glutaraldehyde iyisibulala-magciwane esisebenza kahle kakhulu esibulala amagciwane anhlobonhlobo futhi inconywe iNhlangano Yezempilo Yomhlaba wonke njengesibulala-magciwane esingcolisa i-hepatitis virus.

I-Glutaraldehyde 25%inemiphumela evuselelayo nelaphayo esikhumbeni somuntu kanye nolwelwesi lwamafinyila futhi ingase ibangele ukungezwani komzimba nezinto ezithile, ngakho akufanele isetshenziselwe ukubulala amagciwane emoyeni nezitsha zokudla.Ngaphezu kwalokho, i-glutaraldehyde akufanele isetshenziselwe ukubulala amagciwane kanye nokuvalwa inzalo kwemishini yezokwelapha yamashubhu, izinaliti zomjovo, izinsimbi zokuhlinza kanye nezintambo zikakotini.

I-Glutaraldehyde ivamise ukusetshenziswa njengesibulala-magciwane embonini yezokwelapha futhi abasebenzisi bangase babe nemibuzo ehlobene nezinkinga zobuchwepheshe, ngakho i-Springchem lapha ikunikeza amaphuzu amakhulu mayelana ne-glutaraldehyde ukuze uthole inkomba yakho.

Aukusetshenziswa kwe-glutaraldehyde

I-Glutaraldehyde isetshenziswa njengesibulali magciwane esibandayo ukuze kubulawe amagciwane amathuluzi angezwani nokushisa, njengama-endoscopes kanye nemishini yokuhlanza igazi.Isetshenziswa njengesibulala-magciwane sezinga eliphezulu kulawo mathuluzi okuhlinza angakwazi ukuvalwa amagciwane.

I-Glutaraldehyde isetshenziselwa izicelo eziningana ezikhungweni zezempilo:

● Ithishu elungisa amalebhu e-pathology

● Isibulali magciwane kanye nokuvalwa kwezindawo ezingaphezulu namathuluzi

● I-ejenti eyenza ukuqina esetshenziselwa ukwenza ama-X-ray

● Ukuze kulungiswe ama-graft

Ukuphelelwa yisikhathiusuku lwe-glutaraldehyde nokuthi unganquma kanjani ukuphelelwa yisikhathi

Ezingeni lokushisa lasekamelweni nangaphansi kwesimo sokuba kude nesitoreji esikhanyayo nesivaliwe, usuku lokuphelelwa yisikhathi kwe-glutaraldehyde akufanele lube ngaphansi kweminyaka emi-2, futhi okuqukethwe kwesithako esisebenzayo se-glutaraldehyde kufanele okungenani kube ngu-2.0% phakathi nosuku lokuphelelwa yisikhathi.

Ezingeni lokushisa lasekamelweni, ngemva kokwengeza i-rust inhibitor kanye ne-pH adjuster, i-glutaraldehyde isetshenziselwa ukucwiliswa kwemishini yezokwelapha yokubulala amagciwane noma ukuvala inzalo, futhi ingasetshenziswa izinsuku eziyi-14 eziqhubekayo.Okuqukethwe kwe-glutaraldehyde kufanele okungenani kube ngu-1.8% ngesikhathi sokusetshenziswa.

Ukucwiliswadukuthelelekaindlelange-glutaraldehyde

Gcoba amathuluzi ahlanziwe ku-2.0% ~ 2.5% ye-glutaraldehyde disinfection solution ukuze uwacwilise ngokuphelele, bese uvala isitsha sokubulala amagciwane ekamelweni lokushisa amaminithi angu-60, bese ugeza ngamanzi angenalutho ngaphambi kokusetshenziswa.

Amathuluzi okuxilongwa nawokwelashwa ahlanziwe futhi omisiwe, amathuluzi nezindatshana kufakwa ku-2% yesisombululo se-alkaline glutaraldehyde esicwiliswe ngokuphelele, futhi amabhamuza omoya angaphezulu kwezinsimbi kufanele asuswe nesiqukathi esimbozwe ekushiseni okungama-20 ~ 25℃.Ukubulala amagciwane kusebenza kuze kufike isikhathi esibekiwe semiyalelo yomkhiqizo.

Izidingo zokukhipha amagciwane kuma-endoscopes nge-glutaraldehyde

1. Izinga eliphezulu lokubulala amagciwane kanye nemingcele yokuvala inzalo

● Ukugxila: ≥2% (i-alkaline)

● Isikhathi: isikhathi sokucwiliswa kwe-bronchoscopy disinfection ≥ 20min;ezinye i-endoscopes disinfection ≥ 10min;ukucwiliswa kwe-endoscopic kweziguli ezine-mycobacterium tuberculosis, ezinye i-mycobacteria nezinye izifo ezikhethekile ≥ 45min;ukuvala inzalo ≥ 10h

2. Sebenzisa indlela

● Umshini wokuhlanza i-endoscope kanye nokubulala amagciwane

● Ukusebenza mathupha: isibulala-magciwane kufanele sigcwaliswe ngepayipi ngalinye futhi sicwiliswe ukuze kubulawe amagciwane

3. Izinyathelo zokuphepha

I-Glutaraldehyde 25%i-allergenic futhi iyacasula isikhumba, amehlo nokuphefumula, futhi ingabangela i-dermatitis, i-conjunctivitis, ukuvuvukala kwamakhala kanye ne-asthma yomsebenzi, ngakho-ke kufanele isetshenziswe kumshini wokuhlanza i-endoscope kanye nomshini wokubulala amagciwane.

Izinyathelo zokuphepha nge-glutaraldehyde

I-Glutaraldehyde iyacasula esikhumbeni nakumafinyila futhi inobuthi kubantu, futhi isisombululo se-glutaraldehyde singabangela umonakalo omkhulu emehlweni.Ngakho-ke, kufanele ilungiswe futhi isetshenziswe endaweni enomoya omuhle, ukuvikela komuntu siqu kufanele kulungiselelwe kahle, njengokugqoka imaski yokuzivikela, amagilavu ​​okuzivikela kanye nezibuko zokuzivikela.Uma uthintwe ungaqondile, kufanele ugezwe ngokushesha futhi ngokuqhubekayo ngamanzi, futhi ukunakekelwa kwezokwelapha kusenesikhathi kufanele kufunwe uma amehlo elimele.

Kufanele isetshenziswe endaweni enomoya omuhle, futhi uma kunesidingo, indawo kufanele ibe nemishini yokukhipha umoya.Uma ukugcwala kwe-glutaraldehyde emoyeni endaweni okusetshenziswa kuyo kuphezulu kakhulu, kutuswa ukuthi kufakwe amathuluzi okuphefumula azimele (imaskhi evikela ingcindezi).Izitsha ezisetshenziselwa ukucwiliswa emanzini kufanele zihlanzeke, zimbozwe futhi zibulawe amagciwane ngaphambi kokusetshenziswa.

Ukuqapha imvamisa yokuhlushwa kwe-glutaraldehyde

Ukugxila okusebenzayo kwe-glutaraldehyde kungagadwa ngemichilo yokuhlola amakhemikhali.

Enqubweni yokusetshenziswa okuqhubekayo, ukuqapha kwansuku zonke kufanele kuqiniswe ukuze kubambe izinguquko zokugxila kwayo, futhi akufanele kusetshenziswe uma ukugxila kwayo kutholakala ngaphansi kokugxila okudingekayo.

Kufanele kuqinisekiswe ukuthi ukugcwala kwe-glutaraldehyde okusetshenziswayo kuhlangabezana nezidingo zemanuwali yomkhiqizo.

KufaneleI-glutaraldehyde kufanele icushwe ngaphambi kokusetshenziswa?

Isixazululo esinamanzi se-glutaraldehyde sine-asidi futhi ngokuvamile asikwazi ukubulala izinhlamvu ezihlumayo esimweni esine-asidi.Kulapho kuphela isisombululo “senziwe” nge-alkalinity sibe yinani le-pH lika-7.5-8.5 lapho singabulala khona izinhlamvu.Uma sezicushiwe, lezi zixazululo ziba nempilo yeshelufu okungenani yezinsuku eziyi-14.Emazingeni e-alkaline pH, ama-molecule e-glutaraldehyde athambekele ekubeni enze i-polymerize.I-polymerization ye-glutaraldehyde iphumela ekuvaleni kweqembu le-aldehyde lesayithi elisebenzayo le-molecule yayo ye-glutaraldehyde ebhekene nokubulala izinhlamvu ezikhulayo, futhi ngaleyo ndlela umphumela we-bactericidal uyancipha.

Izinto ezithinta ukuvalwa inzalo kwe-glutaraldehyde

1. Isikhathi sokugxila kanye nesenzo

Umphumela we-bactericidal uzothuthukiswa ngokwanda kokugxila kanye nokwandiswa kwesikhathi sesenzo.Kodwa-ke, isixazululo se-glutaraldehyde esinengxenye enkulu engaphansi kuka-2% asikwazi ukufeza umphumela othembekile we-bactericidal ezinhlamvu zebhaktheriya, kungakhathaliseki ukuthi sinweba kanjani isikhathi sokubulala amagciwane.Ngakho-ke, kuyadingeka ukusebenzisa isixazululo se-glutaraldehyde esinesiqephu esikhulu esingaphezu kuka-2% ukubulala izinhlamvu zebhaktheriya.

2. I-acidity yesisombululo kanye ne-alkalinity

Umphumela we-bactericidal we-acid glutaraldehyde uphansi kakhulu kunalowo we-alkaline glutaraldehyde, kodwa umehluko uzokwehla kancane kancane ngokukhuphuka kwezinga lokushisa.Ebangeni le-pH 4.0-9.0, umphumela we-bactericidal uyanda ngokukhula kwe-pH;umphumela onamandla we-bactericidal ubonwa ku-pH 7.5-8.5;ku-pH>9, i-glutaraldehyde yenza i-polymerize ngokushesha futhi umphumela we-bactericidal ulahleka ngokushesha.

3. Izinga lokushisa

Ibuye ibe nomthelela we-bactericidal emazingeni okushisa aphansi.Umphumela we-bactericidal we-glutaraldehyde ukhuphuka ngezinga lokushisa, futhi izinga lokushisa elilinganisiwe (Q10) liyi-1.5 kuya ku-4.0 ku-20-60℃.

4. Izinto eziphilayo

I-organic matter yenza umphumela we-bactericidal ube buthaka, kodwa umphumela wezinto eziphilayo kumphumela we-bactericidal we-glutaraldehyde mncane kunalowo wezinye izibulala-magciwane.U-20% we-serum yethole kanye no-1% wegazi eliphelele awunawo umthelela kumphumela we-bactericidal ka-2% we-glutaraldehyde.

5. Umphumela we-Synergistic wama-nonionic surfactants nezinye izici ze-physicochemical

I-Polyoxyethylene enamafutha e-alcohol ether iyi-surfactant engekho-nonionic, futhi ukuzinza nomthelela we-bactericidal kuthuthukiswa kakhulu ngokungeza u-0.25% we-polyoxyethylene ether yotshwala obunamafutha kusixazululo se-glutaraldehyde esakhiwe nge-acid-base glutaraldehyde ethuthukisiwe.I-Ultrasound, imisebe ye-infrared kude ne-glutaraldehyde inomphumela wokuvala inzalo we-synergistic.

I-Springchem, umkhiqizi we-glutaraldehyde ohamba phambili waseChina, uhlinzeka nge-glutaraldehyde 25% kanye no-50% wezimboni, ilabhorethri, ezolimo, ezokwelapha, kanye nezinjongo ezithile zasendlini, ikakhulukazi ukubulala amagciwane kanye nokubulala inzalo endaweni nemishini.Ukuze uthole olunye ulwazi, vele usithinte.


Isikhathi sokuthumela: Aug-16-2022