Konke Okudingeka Ukwazi Nge-Glutaraldehyde

I-Glutaraldehyde 25%inemiphumela evuselelayo nephilisayo esikhumbeni somuntu kanye nasezingxeni zolwelwesi lwamafinyila futhi ingabangela ukungezwani komzimba, ngakho-ke akufanele isetshenziselwe ukubulala amagciwane ezitsheni zomoya nezokudla. Ngaphezu kwalokho, i-glutaraldehyde akufanele isetshenziselwe ukubulala amagciwane kanye nokubulala amagciwane emishini yezokwelapha enamashubhu, izinaliti zomjovo, izindwangu zokuhlinzwa kanye nezintambo zikakotini.

I-Glutaraldehyde ivame ukusetshenziswa njengesibulala-magciwane embonini yezokwelapha futhi abasebenzisi bangase babe nemibuzo ehlobene nezinkinga zobuchwepheshe, ngakho-ke i-Springchem lapha inikeza amaphuzu abalulekile mayelana ne-glutaraldehyde ukuze ubhekisele kuyo.

Aukwenziwa kwe-glutaraldehyde

I-Glutaraldehyde isetshenziswa njengesibulali magciwane esibandayo ukuze kubulawe amagciwane ezintweni ezithinta ukushisa, njenge-endoscopes kanye nemishini yokuhlanza. Isetshenziswa njengesibulali magciwane esisezingeni eliphezulu kulezo zinto zokuhlinza ezingenakuhlanzwa ngokushisa.

I-Glutaraldehyde isetshenziswa ezindaweni eziningana zokunakekelwa kwempilo:

● Umshini wokulungisa izicubu emalabhorethri e-pathology

● Isibulali-magciwane kanye nokubulala amagciwane ezindaweni kanye nemishini

● I-ejenti yokuqinisa esetshenziswa ukwenza ama-X-ray

● Ukulungiselela izithombo

Ukuphelelwa yisikhathiusuku lwe-glutaraldehyde kanye nendlela yokunquma ukuphelelwa yisikhathi

Uma izinga lokushisa legumbi liphansi futhi lingekho endaweni yokugcina ekhanyayo nevaliwe, usuku lokuphelelwa yisikhathi kwe-glutaraldehyde akufanele lube ngaphansi kweminyaka emi-2, futhi okuqukethwe kwesithako esisebenzayo se-glutaraldehyde kufanele okungenani kube ngu-2.0% phakathi nosuku lokuphelelwa yisikhathi.

Ezingeni lokushisa legumbi, ngemva kokufaka i-rust inhibitor kanye ne-pH adjuster, i-glutaraldehyde isetshenziselwa ukubulala amagciwane noma ukubulala amagciwane kudivayisi yezokwelapha, futhi ingasetshenziswa izinsuku ezingu-14 eziqhubekayo. Okuqukethwe kwe-glutaraldehyde kufanele okungenani kube ngu-1.8% ngesikhathi sokusetshenziswa.

Ukucwiliswadukuthelelekaindlelane-glutaraldehyde

Cwilisa amathuluzi ahlanziwe ngesisombululo sokubulala amagciwane esingu-2.0% ~ 2.5% se-glutaraldehyde ukuze uwacwilise ngokuphelele, bese umboza isitsha sokubulala amagciwane ekamelweni lokushisa imizuzu engama-60, bese ugeza ngamanzi ahlanzekile ngaphambi kokusebenzisa.

Amathuluzi okuxilonga nawokwelapha ahlanziwe futhi omisiwe, imishini kanye nezinto ezisetshenziswayo kufakwa kusisombululo se-2% se-alkaline glutaraldehyde esicwiliswe ngokuphelele, futhi amabhamuza omoya ebusweni bamathuluzi kufanele asuswe ngesitsha simbozwe ekushiseni okungu-20~25℃. Ukubulala amagciwane kusebenza kuze kube yisikhathi esibekiwe semiyalelo yomkhiqizo.

Izidingo zokubulala amagciwane kuma-endoscopes nge-glutaraldehyde

1. Amapharamitha okubulala amagciwane aphezulu kanye nokubulala amagciwane

● Ukuhlushwa: ≥2% (i-alkaline)

● Isikhathi: isikhathi sokucwiliswa kwe-bronchoscopy yokubulala amagciwane ≥ imizuzu engama-20; ukususwa kwe-endoscope kwamanye ama-endoscope ≥ imizuzu eyi-10; ukucwiliswa kwe-endoscopic kweziguli ezinesifo sofuba se-mycobacterium, amanye ama-mycobacteria kanye nezinye izifo ezikhethekile ≥ imizuzu engama-45; ukuhlanza inzalo ≥ amahora ayi-10

2. Sebenzisa indlela

● Umshini wokuhlanza nokubulala amagciwane we-endoscope

● Ukusebenza ngesandla: isibulali-magciwane kufanele sigcwaliswe ngepayipi ngalinye bese sicwiliswa ukuze sihlanze amagciwane

3. Izinyathelo Zokuqapha

I-Glutaraldehyde 25%ibangela ukungezwani komzimba futhi iyacasula isikhumba, amehlo kanye nomoya, futhi ingabangela i-dermatitis, i-conjunctivitis, ukuvuvukala kwamakhala kanye ne-asthma yomsebenzi, ngakho-ke kufanele isetshenziswe emshinini wokuhlanza nokuhlanza i-endoscope.

Izinyathelo Zokuqapha Nge-Glutaraldehyde

I-Glutaraldehyde iyacasula isikhumba kanye nolwelwesi lwamafinyila futhi inobuthi kubantu, kanti isixazululo se-glutaraldehyde singadala umonakalo omkhulu emehlweni. Ngakho-ke, kufanele silungiswe futhi sisetshenziswe endaweni enomoya omuhle, ukuvikelwa komuntu siqu kufanele kulungiselelwe kahle, njengokugqoka imaski yokuzivikela, amagilavu ​​​​okuzivikela kanye nezibuko zokuzivikela. Uma ithinteke ngengozi, kufanele ihlanzwe ngamanzi ngokushesha nangokuqhubekayo, futhi kufanele kufunwe usizo lwezokwelapha kusenesikhathi uma amehlo elimele.

Kufanele isetshenziswe endaweni enomoya omuhle, futhi uma kudingeka, indawo kufanele ibe nemishini yokukhipha umoya. Uma izinga le-glutaraldehyde emoyeni endaweni yokusetshenziswa liphezulu kakhulu, kunconywa ukuthi ifakwe imishini yokuphefumula equkethe umfutho (imaski yokuvikela umfutho). Izitsha ezisetshenziselwa ukucwilisa izinto kumele zihlanzeke, zimbozwe futhi zihlanzwe ngamagciwane ngaphambi kokusetshenziswa.

Ukuqapha imvamisa yokuhlushwa kwe-glutaraldehyde

Ukuhlushwa okusebenzayo kwe-glutaraldehyde kungaqashwa ngemichilo yokuhlola yamakhemikhali.

Enkambisweni yokusetshenziswa okuqhubekayo, ukuqapha kwansuku zonke kufanele kuqiniswe ukuze kuqondwe izinguquko zokuhlushwa kwayo, futhi akufanele isetshenziswe uma ukuhlushwa kwayo kutholakale kungaphansi kokuhlushwa okudingekayo.

Kufanele kuqinisekiswe ukuthi ukugcwala kwe-glutaraldehyde okusetshenziswayo kuyahlangabezana nezidingo zencwadi yemiyalelo yomkhiqizo.

Kufanelei-glutaraldehyde kufanele isebenze ngaphambi kokusetshenziswa?

Isixazululo samanzi se-glutaraldehyde sinobuthi futhi ngokuvamile asikwazi ukubulala ama-spores aqhumayo esimweni se-acidic. Kuphela lapho isixazululo "sisebenza" nge-alkalinity enanini le-pH elingu-7.5-8.5 lapho singabulala ama-spores. Uma sesisebenzile, lezi zixazululo zinesikhathi sokuphila seshelufu okungenani izinsuku ezingu-14. Emazingeni e-alkaline pH, ama-molecule e-glutaraldehyde avame ukuba yi-polymerize. I-polymerize ye-glutaraldehyde iphumela ekuvalweni kweqembu le-aldehyde lendawo esebenzayo le-molecule yayo ye-glutaraldehyde elibangela ukubulala ama-spores aqhumayo, ngakho-ke umphumela wokubulala amagciwane uyancishiswa.

Izici ezithinta ukubulala amagciwane kwe-glutaraldehyde

1. Isikhathi sokugxila kanye nesenzo

Umphumela wokubulala amagciwane uzothuthukiswa ngokwanda kokuhlushwa kanye nokwandiswa kwesikhathi sokusebenza. Kodwa-ke, isixazululo se-glutaraldehyde esinengxenye yesisindo esingaphansi kuka-2% asikwazi ukufeza umphumela othembekile wokubulala amagciwane kuma-spores ebhaktheriya, kungakhathaliseki ukuthi singalulwa kanjani isikhathi sokubulala amagciwane. Ngakho-ke, kubalulekile ukusebenzisa isixazululo se-glutaraldehyde esinengxenye yesisindo engaphezu kuka-2% ukubulala ama-spores ebhaktheriya.

2. Isixazululo se-acidity kanye ne-alkalinity

Umphumela wokubulala amagciwane we-acid glutaraldehyde uphansi kakhulu kunowe-alkaline glutaraldehyde, kodwa umehluko uzoncipha kancane kancane ngokushisa okwandayo. Ebangeni le-pH 4.0-9.0, umphumela wokubulala amagciwane uyanda ngokwandisa i-pH; umphumela onamandla kakhulu wokubulala amagciwane ubonakala ku-pH 7.5-8.5; ku-pH >9, i-glutaraldehyde ipholimitha ngokushesha futhi umphumela wokubulala amagciwane ulahleka ngokushesha.

3. Izinga lokushisa

Futhi inomphumela wokubulala amagciwane emazingeni okushisa aphansi. Umphumela wokubulala amagciwane we-glutaraldehyde uyanda ngokushisa, futhi i-coefficient yayo yokushisa (Q10) ingu-1.5 kuya ku-4.0 ku-20-60℃.

4. Izinto eziphilayo

Izinto eziphilayo zenza umphumela wokubulala amagciwane ube buthaka, kodwa umphumela wezinto eziphilayo emphumeleni wokubulala amagciwane we-glutaraldehyde mncane kunowezinye izibulali-magciwane. I-20% ye-calf serum kanye ne-1% yegazi eliphelele azinawo umthelela emphumeleni wokubulala amagciwane we-2% glutaraldehyde.

5. Umphumela wokubambisana kwama-surfactants angewona ama-ionic kanye nezinye izinto ze-physicochemical

I-Polyoxyethylene fatty alcohol ether iyi-surfactant engeyona i-ionic, futhi ukuzinza kanye nomphumela wokubulala amagciwane kuthuthukiswa kakhulu ngokungeza i-0.25% polyoxyethylene fatty alcohol ether kwisisombululo se-glutaraldehyde esakhiwe nge-acid-base glutaraldehyde ethuthukisiwe. I-Ultrasound, imisebe ye-far infrared kanye ne-glutaraldehyde kunomphumela wokubulala amagciwane ohambisanayo.

I-Springchem, inkampani ehamba phambili e-10 ye-glutaraldehyde e-China, inikeza i-glutaraldehyde engu-25% kanye no-50% ngezinjongo zezimboni, zelebhu, zezolimo, zezokwelapha, kanye nezinye izinjongo zasekhaya, ikakhulukazi ukubulala amagciwane kanye nokubulala amagciwane ezindaweni kanye nemishini. Ukuze uthole olunye ulwazi, vele usithinte.