I-Hydroxyacetophenone

I-P-hydroxyacetophenone iyisithako sokunakekelwa kwesikhumba esisebenza ngezindlela eziningi, ikakhulukazi esinomsebenzi wokwenza mhlophe futhi sihlobise ubuso, silwa namagciwane futhi silwa nokuvuvukala, futhi sithobe futhi siduduze. Ingavimbela ukwakheka kwe-melanin futhi inciphise umbala kanye namabala. Njenge-ejenti ebanzi yokulwa namagciwane, ingathuthukisa ukutheleleka kwesikhumba. Ingaphinde ithobise ukucasuka kwesikhumba futhi ifanele isikhumba esibucayi.

1. Ukukhuthaza ukukhiqizwa kwe-bile

Inomphumela we-cholagogic, ingakhuthaza ukukhishwa kwe-bile, isize ekukhipheni i-bilirubin nama-acid e-bile e-bile, futhi inomphumela othile osizayo ekwelapheni i-jaundice kanye nezinye izifo zesibindi ne-gallbladder. Iphinde isetshenziswe ekulungiseleleni imithi ethile, njengemithi ye-choleretic kanye neminye imithi yokwenziwa ephilayo, njengendlela ephakathi kokuhlanganiswa kwemithi.

2. Izakhiwo ze-Antioxidant

Ngoba iqukethe amaqembu e-phenolic hydroxyl,i-p-hydroxyacetophenoneinezakhiwo ezithile ze-antioxidant futhi ivame ukusetshenziswa njenge-antioxidant. Izakhiwo zayo ze-antioxidant kanye ne-antibacterial zombili zivela emaqenjini e-hydroxyl, okwenza kube yi-antioxidant (izimfanelo ze-phenolic kanye ne-ketone). Inezakhiwo ezinamandla ze-antioxidant, ingasusa ama-free radical emzimbeni, ivikele amaseli ekulimaleni kwe-oxidative, futhi ngaleyo ndlela inemisebenzi yokuvimbela izifo kanye nokulwa nokuguga.

3. Ilwa namagciwane kanye nokulwa nokuvuvukala

Isebenza kahle ekulweni nesikhunta, inamandla okubulala i-Aspergillus Niger, futhi inomphumela othile wokuvimbela i-Pseudomonas aeruginosa. Izinzile kahle ngaphakathi kwe-pH ebanzi kanye nokushisa. Inomthelela othile wokwelapha osizayo ezifweni zesikhumba kanye nokuvuvukala.

4. Njengesinongo kanye nesilondolozi

Ivame ukusetshenziswa njengesithuthukisi sokulondoloza (ngokuvamile ihlanganiswa ne-hexanediol, i-pentyl glycol, i-octanol, i-ethylhexylglycerol, njll. ukuze ithathe indawo yezilondolozi zendabuko).I-P-hydroxyacetophenoneivame ukusetshenziswa njengesinongo kanye nesilondolozi, esingandisa impilo yeshelufu yemikhiqizo futhi siyinike amaphunga athile.

5. I-ejenti yokwenza mhlophe

Kusukela "esilondolozini" kuya "esimhlopheni", ukutholakala kwei-p-hydroxyacetophenoneisibonisile ukuthi ezinye izinto zokusetshenziswa ezimonyweni zingase zisenamakhono amaningi angakasetshenziswa.

Ingxenye ye-carbonyli-p-hydroxyacetophenoneingangena ngokujulile endaweni esebenzayo ye-tyrosinase, kuyilapho iqembu layo le-phenolic hydroxyl lingakha izibopho ze-hydrogen ezizinzile nezinsalela ze-amino acid ezibalulekile. Le ndlela eyingqayizivele yokubopha iyenza ikwazi “ukukhiya” i-tyrosinase ngokuqinile, ngaleyo ndlela ivimbele ukukhiqizwa kwe-melanin.

Esikhathini esizayo, ngokujula kocwaningo olwengeziwe kanye nokuqongelela kokuqinisekiswa kwemitholampilo,i-p-hydroxyacetophenonekulindeleke ukuthi idlale indima ebaluleke kakhulu emkhakheni wokwenza mhlophe isikhumba kanye nokunakekelwa kwesikhumba, ibe yisithako sokwenza mhlophe isizukulwane esilandelayo esihlanganisa ukuphepha kanye nokusebenza kahle okukhulu.