Wonke umuntu ufisa ukuba nezinwele ezinempilo, kodwa iningi linezinkinga zezinwele ezahlukene. Ingabe ukhathazwa yinkinga yesikhumba esinamaqhubu? Nakuba ugqoka kahle futhi ubukeka kahle, amaqhubu amaningi ayakudambisa noma ayakwethusa nsuku zonke. Amaqhubu ayagqama uma unezinwele ezimnyama noma ugqoke izingubo ezimnyama, ngoba ungase ubone la maqhubu ezinweleni zakho noma emahlombe akho. Kodwa kungani uthola amaqhubu angapheli kuyilapho abanye bengenawo? Ungawunciphisa noma uwususe kanjani amaqhubu ngempumelelo? Impendulo ilula: zama ama-shampoo okulwa namaqhubu aqukethe i-zinc pyrithione.
Kuyini i-dandruff?
Ngokuvumelana nei-zinc pyrithioneNgokusho kwabaphakeli, i-dandruff akuyona nje inkinga yokuhlanzeka komuntu siqu, futhi i-World Health Organisation ifake izinwele ezicwebezelayo kanye nokungabi ne-dandruff ezindinganisweni eziyishumi zezempilo. I-Dandruff, ama-keratinocyte achitheka ekhanda futhi adalwe yingxube yamafutha nemvubelo (isikhunta esibizwa ngokuthi i-Malassezia). Cishe noma ubani angaba ne-dandruff, kodwa ngaphansi kwezimo ezivamile, akekho ongathola i-dandruff enama-keratinocyte amancane achithekile futhi afihliwe kahle. Kodwa njengoba abakhiqizi be-zinc pyrithione besikisela, uma kwenzeka ukucasuka kwangaphandle, inani elikhulu lama-keratinocyte aqoqwe angakakhuli kuze kube sekuvuthweni lizophela. Ukucasuka kwangaphandle kufaka phakathi amafutha aphuma ekhanda kanye ne-Malassezia edla i-sebum, izinto ezinamafutha ezikhiqizwa yizinwele. I-Malassezia ingatholakala esikhumbeni sezilwane nabantu, futhi ayikwazi ukukhula ngaphandle kwe-sebum. Ngakho-ke igxile ekhanda, ebusweni nakwezinye izindawo lapho izindlala ze-sebaceous zisakazeke khona kakhulu.
I-Malassezia inganda ebusweni besikhumba uma ukhiqiza i-sebum eningi, futhi inyuse amazinga ayo ngokuphindwe ka-1.5 kuya ku-2 uma uthola i-dandruff, ngokusekelwe ocwaningweni olwenziwe ngabaphakeli be-zinc pyrithione. Ngaphezu kwalokho, enkambisweni yokubola i-sebum futhi izihlinzeka ngezakhamzimba, i-Malassezia ikhiqiza ne-fatty acid kanye neminye imikhiqizo ehambisana nayo, ngakho-ke izimpendulo zokuvuvukala zizovela uma isikhumba sakho sekhanda sibucayi. Izimpendulo ezivamile zokuvuvukala zifaka phakathi imifantu engajwayelekile kanye ne-dandruff ekhanda, isikhumba sekhanda esilumayo, ama-follicle ezinwele avuvukele, kanye nama-pustules amancane futhi alumayo ekhanda, njll.
Kodwa ungaphazamisi izinwele zakho! Njengoba i-dandruff ibangelwa isikhunta, ukusebenzisa isithako esibulala noma esivimbela ukukhula kwesikhunta ukugeza izinwele zakho kungase kube yindlela nje. Abakhiqizi be-zinc pyrithione bavame ukuncoma abasebenzisi ukuthi bazame ama-shampoo alwa ne-dandruff aqukethe i-zinc pyrithione.
Iyini i-zinc pyrithione?
I-Zinc pyrithione (ZPT), eyaziwa nangokuthi i-pyrithione zinc, iyinkimbinkimbi yokuxhumana ye-zinc ne-pyrithione enezakhiwo zokulwa namagciwane, ezilwa namagciwane, ezilwa ne-fungal, kanye nezokubulala umdlavuza ezingasiza ekubulaleni isikhunta esibangela i-dandruff, zokwelapha i-dandruff, i-scalp psoriasis, kanye ne-acne, futhi ivimbele ukukhula kwemvubelo. Kuyisithako esimhlophe esingancibiliki emanzini, kodwa esincibilikayo ezinyibilikisweni eziphilayo. Ama-formulations aqukethe i-zinc pyrithione asetshenziswe ekwelapheni i-dandruff, i-zinc pyrithione china ingenye yezithako ezisetshenziswa kakhulu zokulwa ne-dandruff emakethe namuhla, kanti ama-shampoo angu-20% aqukethe isithako.
Imininingwane
Ukubukeka: Okumhlophe kuya kokumhlophe okuxutshwe ngamanzi
I-Zinc Pyrithione (% w/w): 48-50% esebenzayo
Inani le-pH (5% isithako esisebenzayo ku-pH 7 amanzi): 6.9-9.0
Okuqukethwe kwe-zinc: 9.3-11.3
Ukusebenza kahle
I-Zinc pyrithione inemiphumela emihle yokulwa ne-dandruff kanye ne-antifungal. Ingavimbela ngempumelelo i-seborrhea futhi yehlise izinga lokuguqulwa kwesikhumba. Njenge-ejenti enomsebenzi wokulwa namagciwane, futhi inomphumela omuhle wokulwa namagciwane futhi inobubanzi bomsebenzi wokulwa namagciwane, kufaka phakathi isikhunta, amabhaktheriya ane-gram-positive kanye ne-gram-negative. Ngokusho kwedatha evela kubahlinzeki be-Zinc pyrithione, ingalwa namabhaktheriya amaningi abangela izifo avela ku-Streptococcus kanye ne-Staphylococcus spp kanye ne-Malassezia furfur, futhi iyi-ejenti ephephile nephumelelayo yokulwa nokulunywa kanye ne-dandruff. Yenziwe ngobuchwepheshe obuphezulu futhi inosayizi omncane wezinhlayiya, i-zinc pyrithione ingavimbela ngempumelelo imvula, iphindaphinde kabili umphumela wayo wokubulala amagciwane, futhi ikusize ukuqeda isikhunta esikhiqiza i-dandruff ngempumelelo enkulu. Ngaphezu kwalokho, i-zinc pyrithione iyinto eyamukelekayo kakhulu yokulwa ne-dandruff yezinwele ezigoqekile, ngoba iholela ekomeni okuncane nasekuqineni.
Umphumela wosayizi wezinhlayiya ze-zinc pyrithione ekhanda
I-Zinc pyrithioneI-China inesimo esiyindilinga kanye nosayizi wezinhlayiya ezingu-0.3˜10 μm. Ukuncibilika kwayo emanzini ku-25° C kungama-15 ppm kuphela. Ukuze kutholakale umphumela wokubambisana, i-zinc pyrithione ingafakwa ezinhlotsheni zezimonyo zokunakekelwa kwezinwele ngenani elingu-0.001˜5% ngesisindo ngokusekelwe esisindweni esiphelele sokwakheka. Usayizi wezinhlayiya ze-zinc pyrithione ziyasiza ekusakazekeni ku-shampoo futhi zihlale zizinzile, zandisa indawo yokuxhumana kanye nenani okufanele lifakwe esikhumbeni uma usebenzisa i-shampoo ukugeza izinwele. Ngenxa yokuncibilika kwayo okuphansi emanzini, izinhlayiya ze-ZPT zingasakazwa kuphela ku-shampoo njengezinhlayiya ezincane. Abakhiqizi be-zinc pyrithione bakhombisa nokuthi i-Zinc pyrithione enobukhulu obuphakathi ingandisa indawo yokuxhumana kanye nembozo enamabhaktheriya kanye nesikhunta esizokhiqiza i-dandruff, futhi ngeke ilahleke ngokuhlanzwa, ngaleyo ndlela ithuthukise ukusebenza kwayo.
Intuthuko kanye nezitayela emakethe
I-Zinc pyrithione iyi-ejenti yokulwa ne-dandruff eyasungulwa futhi yakhiqizwa yi-Arch Chemicals, Inc. yabe isivunyelwa ukusetshenziswa yi-FDA. Njengenye yezithako ezisetshenziswa kakhulu kuma-shampoo okulwa ne-dandruff kanye neminye imikhiqizo yokunakekelwa kwezinwele, i-zinc pyrithione china ngokuqinisekile iyi-ejenti yokulwa namagciwane ephumelela kakhulu futhi ephephile phakathi kwama-agent okulwa ne-dandruff kanye nokulwa nokulunywa atholakala emakethe njengamanje. Kunezinhlobo eziningi zama-shampoo aqukethe i-zinc pyrithione atholakala emakethe. Ungawathola ekhemisi lakho lendawo noma esitolo semithi. Vele uqiniseke ukuthi ufunda uhlu lwezithako ngaphambi kokuthenga, njengoba kungewona wonke ama-shampoo aqukethe i-zinc pyrithione adalwe ngokulinganayo. Eminye imikhiqizo ingaqukatha ezinye izithako ezingaba yingozi ezinweleni zakho noma ekhanda. Abahlinzeki be-zinc pyrithione batusa ukuthi ukhethe ama-shampoo okulwa ne-dandruff anokuqukethwe kwe-zinc pyrithion okungu-0.5-2.0%. Ama-shampoo amele ukulwa ne-dandruff afaka i-P&G's Scalp Care Collection entsha evela eHead & Shoulders, kanye ne-Unilever Clear Scalp & Hair Therapy Shampoo, njll.
Ngokusho kombiko wemakethe i-Zinc Pyrithione Global Forecast To 2028, imakethe yomhlaba wonke ye-zinc pyrithione kulindeleke ukuthi ikhule ku-CAGR engu-3.7% kusukela ngo-2021 kuya ku-2028. Izici zokukhula eziqhuba imakethe yizidingo ezikhulayo zemikhiqizo yezimonyo, ama-shampoo e-dandruff kanye nemikhiqizo yokunakekelwa komuntu siqu, ulwazi olwandisiwe mayelana nempilo kanye nokuhlanzeka, kanye nokwanda kwemali engenayo engasetshenziswa kanye nendlela yokuphila eshintshashintshayo yabantu.
Isikhathi sokuthunyelwe: Ephreli-27-2022