TriclosanIngabe i-antimicrobial ebanzi ebanzi esetshenziswa njenge-antiseptic, i-distinchectate noma okulondolozayo ezilungiselelweni zemitholampilo, imikhiqizo ehlukahlukene yabathengi, imikhiqizo yokuhlanza yasendlini, izindwangu, izindwangu, lapho kungafakwa khona kancane isikhathi eside ngesikhathi sokusebenzisa kwabo, ukwenza lokho isenzo se-biocidal.
I-triclosan isetshenziswa kanjani kwezimonyo?
TriclosanUbhalwe ngo-1986 ku-European Community Community Cosmetics Directive ukuze isetshenziswe njengendawo yokugcina emikhiqizweni yezimonyo ekugxileni kuze kube ngu-0.3%. Ukuhlolwa kobungozi kwakamuva okwenziwe yiKomidi le-EU le-EU ngemikhiqizo yabathengi kuphetha ngokuthi, yize ukusetshenziswa kwalo ekuqoqweni okuphezulu kwe-0.3%, ama-maxitunants okugeza, ama-maxitunant of the aggregant adveased ku-triclosan kuyo yonke imikhiqizo yezimonyo ayiphephile.
Noma yikuphi ukusetshenziswa okwengeziwe kwe-triclosan kuma-powders ubuso kanye namafihla kulolu ntuthuko bekubhekwa futhi kuphephile, kepha ukusetshenziswa kwe-triclosan kweminye imikhiqizo yekhefu (isib. Ama-motion omzimba) futhi ngokwemilomo akuzange kubhekwe kuphephile. Ukuchayeka kwe-inhalation ku-triclosan kusuka kumikhiqizo yokufafaza (isib. Deodorants) akuzange kuhlolwe.
TriclosanUkuba yi-nonic, kungakhiwa kuma-dentifric ajwayelekile. Kodwa-ke, ayibophisi endaweni engaphezulu kwamahora ambalwa, ngakho-ke ayihambisi izinga elifundwayo lomsebenzi wokulwa ne-plaque. Ukwandisa ukufana nokugcinwa kwe-triclosan ngezindawo zomlomo zokwenza ngcono ukulawulwa kwe-plaque kanye ne-gingival Health, Triclosan / Polyvinylmethyl, Triclosan / Zinc Counrate Dentifrice / Calcium Carbonate Dentifrice asetshenzisiwe.
I-triclosan isetshenziswa kanjani ekunakekelweni kwezempilo nakwezokwelapha?
Triclosanisetshenziswe kahle emtholampilo ukuqeda izidalwa ezincane ezifana ne-methicillin-starphylococcus aureus (MRSA), ikakhulukazi ngesincomo sokusebenzisa i-2% Triclosan BATH. I-Triclosan iqashwa njengokuhlinzwa kokuhlinza, futhi isetshenziswa kabanzi ekuhlanzekeni kwezandla nanjenge-body geza ukuqeda i-MRSA kubathwali ngaphambi kokuhlinzwa ngaphambi kokuhlinzwa ngaphambi kokuhlinzwa ngaphambi kokuhlinzwa ngaphambi kokuhlinzwa ngaphambi kokuhlinzwa ngaphambi kokuhlinzwa ngaphambi kokuhlinzwa ngaphambi kokuhlinzwa ngaphambi kokuhlinzwa ngaphambi kokuhlinzwa ngaphambi kokuhlinzwa.
I-Triclosan isetshenziswa kumadivayisi amaningi ezokwelapha, ngokwesibonelo izitokisi ze-ureteral, ama-sutures okuhlinza futhi angahle abhekwe ukuvikela ukutheleleka okuxhumeka. UBojar et al akazange abuke umehluko phakathi kwamakholoni phakathi kwama-suture e-triclosan-camera, yize umsebenzi wawo ukhathazekile amagciwane amahlanu futhi usekelwe kuphela ekunqumeni kwe-zone ye-beading.
Ezitokisini ze-ureteral, i-triclosan ikhonjiswe ukuthi ikhule ukukhula kwamagciwane ajwayelekile ama-bacterial eropathagens futhi anciphise izigameko ze-urinary-tract kanye nama-antibiotics asanda kukhombisa izinhlobo ze-triclosan eziyisikhombisa, futhi zisekela ukusetshenziswa kwe-triclosan-etuting strent lapho kunesidingo, kanye Ukwelashwa okujwayelekile kwama-antibiotic ekwelapheni iziguli eziyinkimbinkimbi.
Kwenye intuthuko, ukusetshenziswa kweTriclosan ku-Urinary Foley Catheter kuphakanyiswe kusukela ku-Triclosan kuvinjelwe ngempumelelo ukukhula kwamaprotheni ama-Mirabilis kanye nokuziphendulela okulawulwayo nokuvinjwa kwe-catheter. Muva nje, Darouiche et al. Kuboniswe i-Synergistic, ebanzi-spectrum kanye nomsebenzi oqinile we-antimicrobial wama-catheters ahlanganiswe nenhlanganisela ye-triclosan kanye ne-dispinb, i-enzym ye-anti-biofilm, ehlakazayo biofilms.
I-Triclosan isetshenziswa kanjani kweminye imikhiqizo yabathengi?
Umsebenzi obanzi we-antimicrobial we-triclosan uholele ekufakweni kwawo ngohlu olunwetshiwe lwezakhiwo zomkhiqizo ezihloselwe ukusetshenziswa kwezakhiwo ezifana nezinsipho eziwuketshezi, ama-detergents, amabhodi okugawula, izingane iziqukathi zokudla. Uhlu olunemininingwane yemikhiqizo yabathengi equkethe i-triclosan ihlinzekwa yi-US Envirol Environmental Protection Agency (EPA) nangeqembu elisebenzayo le-US NGOS "kanye" nangaphandle kwezinambuzane ".
Inani elikhulayo lezinto zokugqoka liphathwa nge-biocides. I-Triclosan ingelinye lama-ejenti wokuqeda ukukhiqizwa kwezindwangu ezinjalo .Izindwangu eziqediwe nge-triclosan ziphathwa ngama-ejenti axhumanisa aqamba ama-antibacterial. Ngokwesisekelo semininingwane etholakalayo, imikhiqizo engu-17 evela emakethe yezitolo zaseDenmark yahlaziywa kokuqukethwe kwezinye izinkwa ze-antibacterial: Triclosan, Dichlorororororban, Triclorororororororban kanye neKathon CG. Imikhiqizo emihlanu yatholakala iqukethe i-0.0007% - 0.0195% Triclosan.
I-Aiello et al ekubuyekezweni kokuqala okuhleliwe okuhlola inzuzo yensipho equkethe i-triclosan, ihlolwe izifundo ezingama-27 ezishicilelwe phakathi kwango-1980 naku-2006. Okukodwa kokutholakele okuqukethe ama-triclosan aqukethe izinsolo ezingezona ze-antimicrobial saps. Izifundo ezisetshenzisiwe zensipho eziqukethe> 1% Triclosan zikhombise ukuncishiswa okukhulu kumazinga athelelekile, imvamisa ngemuva kwezicelo eziningi.
Ukuntuleka okubonakalayo kobudlelwano phakathi kokusetshenziswa kwensipho okuqukethe i-triclosan kanye nokwehliswa kokugula okuthathelwanayo kwakunzima ukuthola ukuthi kungabikho yini ama-biological agents abhekele izimpawu zokugula. Izifundo ezimbili zakamuva ze-US zikhombise ukuthi ukugeza izandla ngensipho ye-antimicrobial equkethe i-triclosan (0.46%) kunciphise umthwalo wegciwane kanye nokudluliselwa kwamagciwane ezandleni, kuqhathaniswa ne-waving
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Isikhathi sePosi: Jun-10-2021