chlorphesesinisetshenziswa ngempela njengokulondolozwa kwezimonyo ngenxa yezakhiwo zayo ze-antiseptic. Kodwa-ke, uma ufuna ukuthuthukisa ukusebenza kwawo njenge-antiseptic, kunezindlela eziningi ezingasetshenziswa. Nazi izindlela ezimbalwa:
Ukuhlanganiswa kwe-Synergistic: I-Chlorphesesin ingahlanganiswa namanye ama-ejenti agciniwe noma ama-antimicrobial agents ukuthuthukisa umphumela wayo we-antiseptic. Ukuhlanganiswa kwe-Synergistic kuvame ukuphumelela ukwedlula ukusebenzisa okukodwa kwedwa. Isibonelo, ingahlanganiswa namanye amakhompiyutha we-Phenol afana ne-thymol noma i-eugenol, noma ngamapharabens, avame ukusetshenziswa njengezimomo ze-cosmetics. Ukuhlanganiswa okunjalo kunganikeza i-spectrum ebanzi yomsebenzi we-antimicrobial.
Ukusebenziseka kahle kwe-Ph: Ukusebenza kwe-antimicrobial kwechlorphesesiningathonywa yi-pH yokwakhiwa. Ama-microorganisms anokubumbana okuhlukile kuma-antiseptics emazingeni ahlukene we-PH. Ukulungisa i-PH yokwakhiwa kwezimonyo kubanga elifanele kungathuthukisa ukusebenza ngempumelelo kwe-chlorphesesin njenge-antiseptic. Lokhu kungatholakala ngokwenza umkhiqizo nge-PH okungathandeki ekukhuleni kwama-microorganisms.
Ukucatshangelwa okwakhiwa: Izakhiwo zenyama nezomakhemikhali zokwakhiwa kwezimonyo zingathinta kakhulu umphumela we-antiseptic we-chlorphesesin. Izici ezinjenge-solubity, ukuhambisana nezinye izithako, futhi ukuba khona kwama-surfactants kungathonya umsebenzi we-antimicrobial. Kubalulekile ukuthi ukhethe ngokucophelela nokwandisa izingxenye zokwakha ukuze kuqinisekiswe ukusebenza okuphezulu kwe-chlorphesesin njenge-antiseptic.
Ukwanda kokuhlushwa: kwandisa ukugxila kwechlorphesesinekwakhekeni kwezimonyo kungakhulisa umphumela wayo we-antiseptic. Kodwa-ke, kubalulekile ukuqaphela ukuthi ukugxila okuphezulu kungahle kuholele ekucasukeni kwesikhumba okukhulayo noma ukuzwela. Ngakho-ke, noma yikuphi ukwanda kokuhlushwa kufanele kwenziwe ngaphakathi kwemikhawulo yokusebenzisa okuphephile futhi kucatshangelwe umthelela ongaba khona ekubekezelelekeni kwesikhumba.
Izinhlelo zokulethwa ezithuthukisiwe: Izinhlelo zokulethwa kwenoveli zingaqashwa ukuze zithuthukise ukungena nokusebenza kahle kwe-chlorphesesin. Isibonelo, ukuncoma kwe-chlorphesesin kuma-liposomes noma ama-nanoparticles angavikela isithako esisebenzayo, alawule ukukhishwa kwawo, futhi athuthukise ukuqina kwawo kanye ne-bioavailability yayo. Lezi zinhlelo zokulethwa zinganikeza ukukhululwa okuqhubekayo kwe-antiseptic, ekwande isenzo sayo kanye nokwenza ngcono ukusebenza kwayo.
Kubalulekile ukuqaphela ukuthi noma yikuphi ukuguqulwa kokuhlelwa noma ukusetshenziswa kwe-chlorphesen kufanele kuhambisane nemihlahlandlela yokulawula namazinga okuphepha. Ngaphezu kwalokho, ukuqhuba ukuqina okufanele kanye nokuhlola ukusebenza kahle kubalulekile ukuze uqinisekise ukuthi ukwakheka okulungisiwe kugcina izakhiwo zayo zokulwa namagciwane ngokuhamba kwesikhathi.
Isikhathi sePosi: Jun-07-2023