i-chlorphenesinisetshenziswa ngempela njengesivimbeli ezimonyoni ngenxa yezakhiwo zayo ezibulala amagciwane.Kodwa-ke, uma ubheka ukuthuthukisa ukusebenza kwayo njenge-antiseptic, kunezindlela ezimbalwa ezingasetshenziswa.Nazi izindlela ezimbalwa:
Inhlanganisela ye-Synergistic: I-chlorphenesin ingahlanganiswa nezinye izilondolozi noma ama-antimicrobial agents ukuze kuthuthukiswe umphumela wayo wokulwa nokuvuvukala.Izinhlanganisela ze-Synergistic zivame ukusebenza kangcono kunokusebenzisa inhlanganisela eyodwa yodwa.Isibonelo, ingahlanganiswa namanye ama-phenolic compounds afana ne-thymol noma i-eugenol, noma nama-parabens, avame ukusetshenziswa njengezilondolozi ezimonyoni.Izinhlanganisela ezinjalo zinganikeza i-spectrum ebanzi yomsebenzi we-antimicrobial.
Ukusebenza kahle kwe-pH: Ukusebenza kahle kwe-antimicrobiali-chlorphenesiningathonywa yi-pH yokwakheka.Ama-microorganisms anokuthambekela okuhlukile kuma-antiseptics kumazinga ahlukene we-pH.Ukulungisa i-pH yokwakheka kwezimonyo ibe uhla olufanele kungathuthukisa ukusebenza kahle kwe-chlorphenesin njengesibulala-magciwane.Lokhu kungafezwa ngokwenza umkhiqizo nge-pH engalungile ekukhuleni kwama-microorganisms.
Ukucatshangelwa kokwakhiwa: Izakhiwo zomzimba kanye namakhemikhali ekwakhiweni kwezimonyo zingaba nomthelela omkhulu kumphumela obulala amagciwane we-chlorphenesin.Izinto ezifana nokuncibilika, ukuhambisana nezinye izithako, kanye nokuba khona kwama-surfactants kungathonya umsebenzi we-antimicrobial.Kubalulekile ukukhetha ngokucophelela kanye nokwandisa izingxenye zokwakheka ukuze kuqinisekiswe ukusebenza kahle okukhulu kwe-chlorphenesin njengesibulala-magciwane.
Ukwanda kokuhlushwa: Ukwandisa ukugxila kwei-chlorphenesinekwakhiweni kwezimonyo kungathuthukisa umphumela wayo we-antiseptic.Kodwa-ke, kubalulekile ukuqaphela ukuthi ukugxila okuphezulu kungase kubangele ukwanda kokucasuka noma ukuzwela kwesikhumba.Ngakho-ke, noma yikuphi ukwanda kokugxila kufanele kwenziwe ngaphakathi kwemikhawulo yokusetshenziswa ephephile futhi kucatshangelwe umthelela ongaba khona ekubekezeleni kwesikhumba.
Amasistimu okulethwa athuthukisiwe: Amasistimu okulethwa amanoveli angasetshenziswa ukuthuthukisa ukungena nokusebenza ngempumelelo kwe-chlorphenesin.Isibonelo, i-encapsulation ye-chlorphenesin ku-liposomes noma i-nanoparticles ingavikela isithako esisebenzayo, ilawule ukukhululwa kwayo, futhi ithuthukise ukuzinza kwayo kanye ne-bioavailability.Lezi zinhlelo zokulethwa zinganikeza ukukhululwa okuqhubekayo kwe-antiseptic, kwandise ukusebenza kwayo futhi kuthuthukise ukusebenza kwayo.
Kubalulekile ukuqaphela ukuthi noma yiziphi izinguquko ekwenziweni noma ekusetshenzisweni kwe-chlorphenesin kufanele zihambisane nemihlahlandlela yokulawula kanye namazinga okuphepha.Ukwengeza, ukwenza ukuhlolwa kokuqina nokusebenza ngempumelelo kubalulekile ukuze kuqinisekiswe ukuthi ukwakheka okuguquliwe kugcina izici zayo zokulwa namagciwane ngokuhamba kwesikhathi.
Isikhathi sokuthumela: Jun-07-2023