I-Climbazolekanye ne-Piroctone Olamine kokubili izithako ezisebenzayo ezivame ukusetshenziswa ekwakhiweni kwe-shampoo ukulwa ne-dandruff.Nakuba behlanganyela izici ezifanayo ze-antifungal futhi bahlose imbangela efanayo eyisisekelo ye-dandruff (ukhunta i-Malassezia), kukhona umehluko phakathi kwalezi zinhlanganisela ezimbili.
Umehluko owodwa oyinhloko usendleleni yazo yokwenza.I-ClimbazoleIsebenza ngokuyinhloko ngokuvimbela i-biosynthesis ye-ergosterol, ingxenye eyinhloko ye-fungal cell membrane.Ngokuphazamisa ulwelwesi lwamangqamuzana, i-cliazole ibulala ukhunta ngempumelelo futhi inciphisa inkwethu.Ngakolunye uhlangothi, i-Piroctone Olamine isebenza ngokuphazamisa ukukhiqizwa kwamandla ngaphakathi kwamangqamuzana esikhunta, okuholela ekufeni kwawo.Iphazamisa umsebenzi we-mitochondrial we-fungus, iphazamise amandla ayo okukhiqiza amandla futhi iphile.Lo mehluko ezindleleni uphakamisa ukuthi angase abe namazinga ahlukahlukene okusebenza ngokumelene nezinhlobo ezahlukene ze-Malassezia.
Omunye umehluko ophawulekayo yizici zabo zokuncibilika.I-Climbazole incibilika kakhulu emafutheni kunamanzi, okuyenza ifaneleke ukwakhiwa kweshampu yohlobo olususelwa kuwoyela noma i-emulsion.I-Piroctone Olamine, ngakolunye uhlangothi, incibilika kakhulu emanzini, ivumela ukuthi ifakwe kalula kuma-shampoos asekelwe emanzini.Ukukhetha phakathi kwe-clikazole ne-Piroctone Olamine kungase kuncike ekwakhekeni okufunayo kanye nezintandokazi zomenzi.
Mayelana nokuphepha, kokubili i- climbazole ne-Piroctone Olamine inerekhodi elihle elinemiphumela emibi emincane.Kubhekwa njengokuphephile ukusetshenziswa kwezihloko, nakuba ukuzwela komuntu ngamunye noma ukungezwani komzimba kungase kwenzeke.Kuhlale kunconywa ukuthi ulandele imiyalelo futhi uthintane nochwepheshe bezempilo uma kukhona ukusabela okungekuhle.
Ukwakhiwa kwe-shampoo kuvame ukuhlanganisakhuphukazolenoma i-Piroctone Olamine nezinye izithako ezisebenzayo ukuze kuthuthukiswe ukusebenza kahle kwazo ngokumelene ne-dandruff.Ngokwesibonelo, zingase zihlanganiswe ne-zinc pyrithione, i-selenium sulfide, noma i-salicylic acid ukuze kunikeze indlela ebanzi yokulawula inkwethu.
Kafushane, kuyilapho kokubili i-climpazole ne-Piroctone Olamine kuyizinto ezisebenzayo ze-antifungal ezisetshenziswa ekwenziweni kwe-shampoo, ziyahlukahluka ezindleleni zazo zokusebenza kanye nezakhiwo zokuncibilika.Ukukhetha phakathi kwakho kokubili kungase kuncike ekukhethweni kokubunjwa kanye nezici ezifiselekayo zomkhiqizo we-shampoo.
Isikhathi sokuthumela: Jun-13-2023