Ingabe i-phenoxyethanol iyingozi esikhumbeni?

Kuyinii-phenoxyethanol?
I-Phenoxyethanol iyi-glycol ether eyakhiwe ngokuhlanganisa amaqembu e-phenolic ne-ethanol, futhi ibonakala njengamafutha noma i-mucilage esimweni sayo soketshezi. Iyisivikelo esivamile ezimonyweni, futhi ingatholakala kukho konke kusukela kokhilimu bobuso kuya kokhilimu.
I-Phenoxyethanol ifinyelela umphumela wayo wokulondoloza hhayi nge-antioxidant kodwa ngomsebenzi wayo wokulwa namagciwane, okuvimbela futhi ususe ngisho nemithamo emikhulu yamagciwane angema-gram-positive kanye nama-negative. Iphinde ibe nomthelela omkhulu wokuvimbela ezinhlobonhlobo zamagciwane avamile njenge-E. coli kanye ne-Staphylococcus aureus.
Ingabe i-phenoxyethanol iyingozi esikhumbeni?
I-Phenoxyethanol ingaba yingozi uma igwinywa ngamanani amakhulu. Kodwa-ke, ukusetshenziswa kwangaphandle kwe-phenoxyethanol kungaba yingozi uma igwinywa ngamanani amakhulu.i-phenoxyethanolekugxilweni okungaphansi kuka-1.0% kusesebangeni eliphephile.
Sesixoxe ngaphambilini ukuthi i-ethanol iguqulwa ibe yi-acetaldehyde ngobuningi esikhumbeni nokuthi ngabe imuncwa ngobuningi yisikhumba. Zombili lezi zibaluleke kakhulu futhi kwi-phenoxyethanol. Esikhumbeni esinomgoqo ophelele, i-phenoxyethanol ingenye yama-glycol ethers ashesha kakhulu ukwehlisa. Uma indlela ye-metabolic ye-phenoxyethanol ifana neye-ethanol, isinyathelo esilandelayo ukwakheka kwe-acetaldehyde engazinzile, kulandelwe yi-phenoxyacetic acid kanye nama-free radicals.
Ungakhathazeki okwamanje! Lapho sixoxa nge-retinol ngaphambili, sikhulume nangohlelo lwe-enzyme oluhlotshaniswa nokusetshenziswa kwe-metabolismi-phenoxyethanol, nokuthi lezi zinqubo zokuguqulwa zenzeka ngaphansi kwe-stratum corneum. Ngakho-ke sidinga ukwazi ukuthi ingakanani i-phenoxyethanol emuncwa ngempela nge-transdermal. Kokunye ukuhlola okwahlola ukumuncwa kwe-sealant esekwe emanzini equkethe i-phenoxyethanol nezinye izithako zokulwa namagciwane, isikhumba sengulube (esinokungena okusondele kakhulu kubantu) singamunca i-phenoxyethanol engu-2%, nayo eyakhula yaba ngu-1.4% kuphela ngemva kwamahora ayi-6, kanye no-11.3% ngemva kwamahora angama-28.
Lezi zifundo ziphakamisa ukuthi ukumuncwa nokuguqulwa kwei-phenoxyethanolUma amazinga angaphansi kuka-1% awanele ukukhiqiza imithamo eyingozi yama-metabolites. Imiphumela efanayo itholakale nasezifundweni ezisebenzisa izinsana ezisanda kuzalwa ezingaphansi kwamasonto angama-27. Ucwaningo luthi, "Amanzii-phenoxyethanolayibangeli umonakalo omkhulu wesikhumba uma kuqhathaniswa nezilondolozi ezisekelwe ku-ethanol. I-Phenoxyethanol iyamuncwa esikhumbeni sezinsana ezisanda kuzalwa, kodwa ayakhi umkhiqizo we-oxidation i-phenoxyacetic acid ngamanani amakhulu." Lo mphumela ukhombisa nokuthi i-phenoxyethanol inesilinganiso esiphezulu kakhulu se-metabolism esikhumbeni futhi ayibangeli umonakalo omkhulu. Uma izingane zingakwazi ukubhekana nakho, yini oyesabayo?
Ubani ongcono, i-phenoxyethanol noma i-alcohol?
Nakuba i-phenoxyethanol ishintshwa ngokushesha kune-ethanol, ukuhlushwa okuphezulu okulinganiselwe kokusetshenziswa kwangaphandle kuphansi kakhulu ku-1%, ngakho-ke akulona ukuqhathanisa okuhle. Njengoba i-stratum corneum ivimbela iningi lama-molecule ukuthi angamuncwa, ama-free radical akhiqizwa yilawa amabili mancane kakhulu kunalawo akhiqizwa ukusabela kwawo kwe-oxidation nsuku zonke! Ngaphezu kwalokho, ngoba i-phenoxyethanol iqukethe amaqembu e-phenolic ngesimo samafutha, iyahwamuka futhi yome kancane kancane.
Isifinyezo
I-Phenoxyethanol iyisivikelo esivamile esisetshenziswa ezimonyweni. Iphephile futhi isebenza kahle, futhi ilandela ama-parabens kuphela ngokusetshenziswa. Nakuba ngicabanga ukuthi ama-parabens nawo aphephile, uma ufuna imikhiqizo engenama-parabens, i-phenoxyethanol iyisinqumo esihle!